Press Release / Health and Fitness / Improved, traceable membrane protein production in E.coli through tandem fusions and strain evolution

Improved, traceable membrane protein production in E.coli through tandem fusions and strain evolution

Membrane protein expression remains a bottleneck in its characterization and structure determination. In a recent study, scientists created a robust strategy to increase the probability of membrane protein overexpression by generating a traceable fusion system at the C-terminus of their target protein, showing that manipulation of transcriptional silencing improved membrane protein overexpression.

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